Voynichese's letters

[ololololo]

My question is, is there a possibility that the cipher of the manuscript is based on numbers (in particular, Roman ones)?

Yes, it is possible, i see no reason why voynichese could not be based on numbers.

The resemblance of EVA-'iiin' and family to the Roman Numerals II, III, IIV, etc, have oft  been remarked upon but idk of any deep attempts to link the two.   

My light play with the idea
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Roman numerals to Voynicheesy

post by ReneZ about his mod2 cipher system but the links in that post are dead.
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A short post by Elmar Vogt about Cistercian numerals
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J.K.Petersens blog "Voynich portal" has a couple of posts about the similarites between voynichese and Greek and Roman numerals.
/a-helping-hand/  and  /running-the-numbers/
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Thank you very much! Well, I've looked at all the links, and it seems to me that my approach will be closer to yours. I once also tried to match the letters of the manuscript with Roman numerals, but in the end I fell into empty speculation. Of these, I managed to calculate e = 10, a = 5 and ch = 50, the rest I equated to Arabic, and as always, I did not find a place for the gallows. But I don't consider the failures of a layman to be an argument against, and i'm sure that the encryption with numbers is quite possible for the 15th century.