I found another "poxleber"

[Bernd]

Good find!
It's again in the usual context: Vulgar anti-clerical reformation-era satire of the 1520s. A nobleman and a monk, both displaced by the German Peasants’ War lament their fate.
There's also 'pox filtzhüt' on the same page.

I briefly investigated Georg Motschiedler, but he's far less prominent than Hans Sachs or Niklaus Manuel. He appears to have been an amateur writer who's only known from this pamphlet. It's not a play. Little else is known about him. I also haven't found a direct connection between those authors. Pamphlets spread rapidly back then so it's hard to say if those pox- swearwords were just common expressions of the time or if the authors copied from each other. It may very well be that the reformation authors were the first who dared to publish such expressions, while they have a much longer oral history.