Use of "ee" in Q2-3 is weird(?)

[Bluetoes101]

There are only 17 occurrences of  ee in quire 2. Their distribution is within the bounds of statistical acceptability. In quire 3 ( 78 occurrences ) the distribution is ~7.5 standard deviations away from would be expected if the words of that quire were distributed randomly. But you also get much the same with  eo. And also with words ending  y. See the attached simulations output.

But this is not unusual. Many similar distributions of many other parameters in many other sections of the manuscript all show a similar property of being outside the bounds of what would be expected.

( Data from GC transliteration. Paragraph text only. No labels, circulars, radials, nor any 'Pb' text, and with characters 101-C converted to  ee ).

What are examples of other pairings showing this pattern?