I had never seen this manuscript and I agree it is very voynich-esque.
I think that the plant roots and the colour annotations are the most interesting connection, especially little things like this

(perhaps Marco could tell us what this means?).
I personally think that the VMS had more colour annotations and general writing within the roots and leaves (like this manuscript) before much of it was painted over.
There are also some large red capitular which appear in combination with the smaller more common pilcrows, like that of VMS f1r.
Do we have a more concrete date than 15th century for this MS? Do we know which tradition this manuscript is taking its plants from?