Hi Emma,
in my opinion, the most likely scenario is that we will only know what we can get from the manuscript.
There are examples like You are not allowed to view links.
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Login to view., the illustrator of the 1420 ca Roccabonella / Rinio herbal (Venezia, Bibl. Naz. Marciana, Ms. lat.,cl. V, 59[=2548]) and Pennsylvania, You are not allowed to view links.
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Login to view. (recently discussed on You are not allowed to view links.
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Login to view.). His name is only known because it is mentioned in the prologue of the Roccabonella ms. On the other hand, the commissioner Nicolò Roccabonella is relatively well documented.
I think Manfredus De Monte Imperiale, author of Paris, You are not allowed to view links.
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Login to view., early XIV Century, is only known by what he wrote of himself in the first lines of his own work.
The same holds for You are not allowed to view links.
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Login to view., who in 1441 produced another illustrated herbal (Bergamo, Codex MA 592).
In the case of the alchemical herbal, a single manuscript (Vicenza, Bertoliana 362, I think, I should check Segre-Rutz) attributes the work to one Orgiani Rizzardo (or Rizzardo from Orgiano), but the attribution is in a later hand, so in this case also the name is doubtful.
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Login to view., 1300 ca, was usurped by one You are not allowed to view links.
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Login to view. from Siena: a few people with this name have been traced in various records, but it is not clear if any of them might be the right person. Anyway, Bartholomaeus erased the name of the true author, so we will never know who wrote the manuscript.