The ice cube on f102v

[BessAgritianin]

The evidence for late coloring is the folio number on page f42r.  According to Rene and another person who looked at that number with a microscope, the green paint is sitting on top of the ink of the number.  And it seems to be established that the folio numbers were written after the bifolios were bound (in the wrong order), a century of more after the text and drawings were made.

All the best, --stolfi

The Mc Crone analysis was a prove that the pigments are authentic to 15 century, this refutes the claim that they are 20 century edition and also the person painting them might have not been ignorant of their meaning.

Crucially the paint transferring of facing pages proves the colores were applied, while the manuscript was bound. 
Regardless whether the paint had been applied in 1420 or 1450- the blue vitriol on page 102v is based on visual encoding of blue and yellow.