Well used?

[Mark Knowles]

I just watched a recent YouTube video by Paul Whitewick. He seems to be saying that according to Lisa Fagin Davis the Voynich manuscript was well-used by the people who created the manuscript. That might well have been the case, but I am curious as to whether we can really say that with confidence. Can we distinguish between wear and tear from around the time that the manuscript was created and wear and tear that has resulted from the many people who have studied the manuscript at later times?