The oddities of the bigram "ed"

[Skoove]

Very interesting. It always struck me that "ed" is the only bigram that appears by itself in the central "star" of f69r, together with y, d, o, l, s.

I was just about to add this! I think that this might be part of the clue. Perhaps 'ed' is not actually a bigram in some of these quires but is thought of as a single glyph similar to how 'qo' (except 'qo' shows this behaviour over the entire manuscript). This would explain why it occurs so frequently compared to other bigrams.