initial characters, to be last? right-to-left handwritting?

[quimqu]

I agree that the right-to-left writing does not seem to be the scenario, but it could explain the overlapping of the first and second character.

Nevertheless, what intrigued me more is the overlapping in a left-to-right writing pattern, as there is no reason to overlap if the first characters column was written first. So my logic tells me that the column was written at the end. Why do so?

There are so many instances of irregular spacing and smaller glyphs apparently for no reason next to a large space...

There is evidence of bottom-to-top writing (baseline deviations to avoid gallows intrusions from the line below).

Right-to-left writing: I don't see any evidence, maybe in some cases some inserts as these squeezed glyphs seem to indicate, but the alignment on the left in paragraphs is consistent with left-to-right writing.